analgesic role of premative Oral Melatonin before thoracic epidural in bilateral multiple fracture ribs

Role of addition of Oral Melatonin in thoracic epidural analgesia in pain control for patients with bilateral multiple fracture ribs

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR201711002741378

Enrollment

Registered

2017-11-02

Start date

2017-11-04

Completion date

Unknown

Last updated

2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Injury, Occupational Diseases, Poisoning pain in patients with bilateral multiple fracture ribs

Interventions

Placebo group

melatonin group

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 80 ASA Physical status I &II, 18-50 years presented with bilateral fracture ribs.

Exclusion criteria

Exclusion criteria: ¿ Schizophrenia or other psychotic disorder or cognitive impairment ¿ History of drug dependency or substance addiction ¿ A known sensitivity to melatonin or pregabalin, ¿ known to be allergic to any medicines ¿ History of drug or alcohol abuse, taking opioids or sedative medications, and had a history of psychiatric conditions. ¿ Patients with a history of taking pregabalin or gabapentin ¿ pathological rib fractures, kyphoscoliosis ¿ BMI 30 kg m2 ¿ history of cerebro-vascular disease, seizure disorders, central nervous system diseases ¿ coagulation disorders ¿ local skin infection at the side of injection

Design outcomes

Secondary

Measure	Time frame
the severity of pain	—

Primary

Measure	Time frame
the time for the first request for rescue analgesia	—

Countries

Egypt

Contacts

Public Contactnada Omara

Dr.nada.emera@gmail.com01118342012

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Feb 4, 2026