Anti-inflammatory Effect of General Anesthesia plus Supraclavicular Peripheral Nerve Blocks After Distal Humeral and Elbow Surgery: Clinical and Labo

Anti-inflammatory Effect of General Anesthesia plus Supraclavicular Peripheral Nerve Blocks After Distal Humeral and Elbow Surgery: Clinical and Laboratory Comparison versus General Anesthesia Alone

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR201711002713192

Enrollment

Registered

2017-10-21

Start date

2017-08-31

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Injury, Occupational Diseases, Poisoning Surgery post operative pain in upper limb ORIF in limb fractures Anaesthesia

Interventions

General anesthesia alone

General Anesthesia plus Supraclavicular blocks

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Sixty Patients of both genders ASA ( I¿II - III), aged from 18 to 75 years will be randomly allocated either to receive general anesthesia alone (20) patients group GA , or general anesthesia + supraclavicular block (GAB) (30) patients.

Exclusion criteria

Exclusion criteria: Exclusion criteria include previous surgery or trauma on the upper limb, current use or previous use of corticosteroids, systemic illness known to affect the inflammatory changes such as rheumatoid arthritis, patients with Congestive heart failure, diabetes mellitus, hypertension, malignancy , patients with coagulopathies or on anticoagulants or antiplatelet therapy.

Design outcomes

Primary

Measure	Time frame
cytokine response (inflammatory:IL-6), (TNF-¿ and anti-inflammatory(IL-10) ) ;5-Morphine consumption	—

Secondary

Measure	Time frame
1- The circumference and skin temperature of the operated site and contralateral side. ;2- Oedema will be measured thread and compared witth the contralateral side and by oedema score.;3- Pain at rest and at movement will be measured by (VAS) from (0¿10) measured ;4- Healing power of wound: Assessment by Bates-Jensen wound assessment tool (1-13)	—

Countries

Egypt

Contacts

Public ContactAtef Mohamed Sayed Khalil

Lecturer of Anesthesiology Fayoum University

dr.atef.khalil@gmail.com020-084-01016581609

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026