Propofol versus insulin for myocardial protection assessed by ventricular biopsy and troponin I

Propofol versus insulin in cold cardioplegia for myocardial protection assessed by ventricular biopsy and troponin I in cases of on pump valvular cardiac surgery

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR201710002696183

Enrollment

Registered

2017-10-16

Start date

2015-03-15

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

on pump valvular cardiac surgery Cardiology

Interventions

drugs(cold blood cardioplegia in a ratio of 4:1.)

drug 10 IU of regular insulin for each one liter cold blood cardioplegic solution

drug 9 mg of propofol 10% added to cold blood cardioplegia

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: -adult patients - aged between 18 to 60 years - of either sex - American society of Anesthiologist (ASA) physical status II and III -scheduled for elective on pump valvular cardiac surgery.

Exclusion criteria

Exclusion criteria: 1) Previous cardiac surgery (redo). 2) Combined CABG and valvular cardiac surgery. 3) Emergency operation. 4) Chronic renal failure on dialysis. 5) Current congestive heart failure. 6) Poor Left ventricular (LV) function (i.e. LV function <30% ). 7) Diabetic patients . 8) Elevated serum troponin I levels.

Design outcomes

Primary

Measure	Time frame
myocardial protection assessed by lt papillary biopsy and tropinin I	—

Countries

Egypt

Contacts

Public ContactOmyma mohamed

Assistant Professor of Anesthesiology and I.C.U. Faculty of Medicine- Minia University.

omyma.shehata44@yahoo.com01061762894

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026