Pregnancy and Childbirth Fertility-female recurrent abortion
Conditions
Interventions
Nifedipine
sildenafil
control
Sponsors
Menoufia university hospital
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Unexplained recurrent miscarriages of three times or more fathered by the same husband (proved by laboratory documents). Having no living children. range (18 ¿ 35) years. 4. Having had regular menstrual cycles in the three months preceding enrollment. 5. Using neither hormonal contraception nor an intrauterine device.
Exclusion criteria
Exclusion criteria: Women having anatomical uterine abnormalities such as septate uterus, 3rd degree RVF or pathological uterine abnormalities such as myoma or endometrioma on transvaginal ultrasonography. 2. Systemic diseases that may affect hemodynamic indices. 3. A history of oophorectomy or tubal ligation. 4. The presence of side effects or contraindications to both nifedipine and sildenafil citrate. 5. The occurrence of pregnancy during the first study cycle.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| uterine artery blood flow changes and endometrial thickness following the intake of medications. | — |
Secondary
| Measure | Time frame |
|---|---|
| medication side effects. | — |
Countries
Egypt
Contacts
Public ContactNabih Elkhouly
obstetrics and gynecology department, faculty of medicine Menoufia university
Outcome results
None listed