knee osteoarthritis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1- Patients with established clinical and radiological diagnosis of chronic osteoarthritis (OA) who failed to respond to multimodal medical treatment including a combination of systemic and topical nonsteroidal anti-inflammatory drugs (NSAIDs) and pregabalin. 2- Age > 50 year. 3- Female patients. 4- Unilateral or bilateral knee pain
Exclusion criteria
Exclusion criteria: 1- Patient refusal. 2- Patients with coagulopathy. 3- Patients having local infection at the site of injection. 4-Patients who cannot comply with the use of VAS. 5-Psychiatric patients or patients on antipsychotic drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| -The frequency of responders to intervention in each of the four study groups at 2 weeks assessment time point. Response to intervention is defined as a 50% or greater decrease in the pain VAS or the WOMAC pain subscale according to a proposal of Outcome Measures in Rheumatology Clinical Trials and Osteoarthritis Research Society International | — |
Secondary
| Measure | Time frame |
|---|---|
| - The severity of knee OA pain using (VAS).;- Knee function will be assessed using the validated WOMAC (Western Ontario and McMaster Universities) Index of Osteoarthritis);- Quadriceps muscle strength and the time to unassisted ambulation and readiness for charge from the outpatient clinic. ;Patient¿s global assessment of improvement | — |
Countries
Egypt
Contacts
asisstant lecturer of anesthesia at faculty of medicine cairo university