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Fentanyl versus Midazolam as additive to Local Anesthetic Mixture for Peribulbar Block during Posterior Segment Surgery in Adult Patients

Fentanyl versus Midazolam as additive to Local Anesthetic Mixture for Peribulbar Block during Posterior Segment Surgery in Adult Patients

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR201708002496243
Enrollment
150
Registered
2017-08-03
Start date
2017-01-03
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Eye Diseases Surgery Eye Block Anaesthesia

Interventions

Eye Block Fentanyl Group
Eye Block Control Group
Eye Block Midazolam Group

Sponsors

Authors
Lead Sponsor
Kasr Al Ainy Hospitals-Cairo University
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: All patients were clinically evaluated for fitness for anesthesia and categorized according to ASA l grade and patients who had co-morbidities underwent preoperative contro and continued on their treatment during postoperative (PO) course.

Exclusion criteria

Exclusion criteria: 1-Patients with impaired orbital/periorbital sensation, 2-Patients had history of bleeding tendency 3-Patients on current anticoagulants or antiplatelets 4-Patients had allergy to local anesthetics, 5-Patients had posterior staphyloma or with axial length >30 mm were excluded from the study.

Design outcomes

Primary

MeasureTime frame
1.Motor block was evaluated using a three point scoring (14). The onset of eyelid and globe akinesia was assessed at 1, 3, 5, 10 and 15 minute and then every 15 minutes after surgery until complete recovery of the block. Duration of block was calculated starting from 15-min after LAM injection till complete recovery.

Secondary

MeasureTime frame
2. Hemodynamic variables were assessed every 15 minutes during the entire procedure and every 30 minutes during the first two postoperative (PO) hours. Hypotension and bradycardia were defined as a 20% decrease in MAP and HR in relation to baseline measures.;3. PO analgesia was assessed by using 11-points Visual Analogue Score (VAS) every hour for 6-hrs PO and was scored as 0 if no pain up to 10 which indicates intolerable pain sensation. PO analgesia was provided as if VAS was >5 in the form of intramuscular injection of diclofenac 75 mg.

Countries

Egypt

Contacts

Public ContactAhmed Shaker

Lecturer of Anesthesia

asragab1@yahoo.com00201003252323

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026