Respiratory Surgery lung surgery
Conditions
Interventions
treatment group
Placebo
Sponsors
Minoufiya University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: adult patients undergoing open lung surgery
Exclusion criteria
Exclusion criteria: patient refusal to enroll, uncompensated heart problem or mean pulmonary artery pressure (MPAP) > 30 mm Hg, severe lung problem [vital capacity (VC) or forced expiratory volume in 1 s (FEV1) < 50% of the predicted values], renal or hepatic insufficiency, coagulopathy or preoperative immuno-suppressant drugs administration. Intraoperative exclusion criteria included failure to keep a satisfactory arterial oxygen saturation(SaO2) and or end-tidal carbon dioxide (EtCO2), failure to preserve appropriate ventilation parameters for 20 min, and inability to keep hemodynamic stability .
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| arterial oxygen tension/fraction of inspired oxygen (PaO2/FIO2) ratio | — |
Secondary
| Measure | Time frame |
|---|---|
| arterial, and central venous blood gases, changes in alveolar and plasma levels of tumor necrosis factor-¿, and interleukin-8 in addition to changes in alveolar cell numbers and albumin concentrations | — |
Countries
Egypt
Contacts
Public Contactkhaled mahmoud
Professor in anesthesiology, Minoufiya faculty of medicine
Outcome results
None listed