EFFECT OF SINGLE-DOSE PREOPERATIVE DEXAMETHASONE ON POSTOPERATIVE PAIN, NAUSEA AND VOMITING FOLLOWING BREAST SURGERY

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR201707002398224

Enrollment

100

Registered

2017-07-01

Start date

2016-07-04

Completion date

Unknown

Last updated

2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Surgery Postoperative pain, nausea and vomiting post-breast surgery

Interventions

Normal saline

Intravenous dexamethasone

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: All ASA I and II patients coming for elective breast surgery

Exclusion criteria

Exclusion criteria: History of allergy to dexamethasone History of gestational diabetes or diabetes mellitus Patients on chronic steroid therapy Immunosuppression and patients on immunosuppressant drugs History of motion sickness and/or previous PONV after any surgical procedure History of peptic ulcer disease Patients with advanced breast disease for palliative procedures (e.g. toilet mastectomy)

Design outcomes

Primary

Measure	Time frame
Incidence and severity of postoperative pain;Incidence and severity of postoperative nausea and vomiting	—

Secondary

Measure	Time frame
Blood glucose levels;Total amount of opioid used in the first 24 hours postop	—

Countries

Ghana

Contacts

Public ContactIRB Administrator's Office Korle Bu Teaching Hospital

Institutional Review Board

rdo@kbth.gov.gh+233 30 266 6766

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Feb 4, 2026