A randomized control trial of two regimens of oral misoprostol solution in induction of labour

Hourly titrated oral misoprostol solution and 2 hourly static oral misoprostol solution in induction of labour: A randomized controlled trial

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR201707002378458

Enrollment

136

Registered

2017-06-26

Start date

2017-04-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pregnancy and Childbirth Induction of labour

Interventions

Hourly titrated oral misoprostol solution

2 hourly static oral misoprostol solution

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Women with live singleton fetuses with cephalic presentation, intact membranes, reactive non-stress test and unfavorable cervices (Bishop¿s score <6) scheduled to undergo induction of labor at term.

Exclusion criteria

Exclusion criteria: Women with pregnancies <37 weeks gestation, intrauterine fetal death, multiple gestations, previous uterine surgery, prelabour rupture of fetal membranes, abnormal non-stress test and any contraindication to vaginal delivery were excluded. Also, women whose parity was greater than 4, who did not give their consent or have prenatal care in this centre were excluded.

Design outcomes

Primary

Measure	Time frame
Rate of successful induction (vaginal delivery within 24 hours)	—

Secondary

Measure	Time frame
induction-delivery interval, oxytocin requirements, caesarean delivery rate, Apgar scores, admission into special baby care unit (SCBU), and occurrence of complications of IOL like fetal heart rate abnormalities, uterine rupture etc	—

Countries

Nigeria

Contacts

Public ContactTolulope Aduloju

Research Nurse/ Social worker

toluy2k200@yahoo.com2348037254033

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026