Sedative regimens for drug induced sleep endoscopy in sleep apnea patients.

Respiratory and hemodynamic effects of three different sedative regimens for drug induced sleep endoscopy in sleep apnea patients. A prospective randomized study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR201706002232945

Enrollment

Registered

2017-04-23

Start date

2017-05-08

Completion date

Unknown

Last updated

2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Drug-Induced Sleep Endoscopy, Obstructive Sleep Apnea

Interventions

propofol

dexmedetomidine

ketofol

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: both sexes aged between 18-50 years old classified as American Society of Anesthesiologists ASA physical status I, II, III, diagnosed as OSAS by clinical criteria(snoring , morning headache, day sleepiness and tiredness) and polysomnography (apnea hypopnea index>5)

Exclusion criteria

Exclusion criteria: 1- Patients who refuse to give informed consent 2- Patients with a baseline oxygen desaturation (resting hypoxemia <95 %) 3- Patients with Mallampati scores of III-IV 4- Patients who are pregnant 5- Patients with frank aspiration history 6- Drug abusers or those having history of chronic anal¬gesic use 7- Patients who known to have allergy against the study drugs, 8- Patients with IInd-IIIrd degree A-V block, pulmonary hypertension ,uncontrolled systemic hypertension, mitral stenosis, aortic stenosis or ischemic heart diseases will be excluded 9- Patients with psychiatric dis¬orders will be also excluded from the study.

Design outcomes

Primary

Measure	Time frame
measurement of the incidence of oxygen desaturation among the three groups. Oxygen desaturation is defined as oxygen saturation <90% for more than 30 s, measured using pulse oximetry(9).	—

Secondary

Measure	Time frame
¿ cough reflex (cough and/or sneezing) incidence	—

Countries

Egypt

Contacts

Public ContactRehab ElKalla

Lecturer of anesthesiology and surgical ICU Faculty of medicine-Tanta University

rehouba10@hotmail.com+201285700765

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Feb 4, 2026