TRIP study

Translating Research into Practice (TRIP): Evaluating and Speeding up the adoption of an evidenced based innovative REMSTART package to reduce mortality in advanced stage HIV patients starting antiretroviral therapy in Tanzania

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR201706002208408

Enrollment

5580

Registered

2017-04-14

Start date

2016-02-29

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

HIV/AIDS Cryptococcal Meningitis

Interventions

Cryptococcal serum antigen screening

Fluconazole

M-health messaging

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The inclusion criteria will be: - CD4<200 cells /¿l - Serum/plasma CrAg positive - Lumbar puncture negative - Adult: ¿18y or more. - Antiretroviral naïve (as reported by the patient) - Planning to remain in the study area for about 6 months (as reported by the patient)

Exclusion criteria

Exclusion criteria: The exclusion criteria will be: - requiring immediate in-patient care / admission - Pregnant or lactating - If ALT > 5 times upper limit of normal

Design outcomes

Primary

Measure	Time frame
All-cause Mortality	—

Secondary

Measure	Time frame
Patient retention on ART;costs of the strategies to the health service ;Assessment of enabling and barrier factors;pattern of re-organization of staffs roles	—

Countries

Tanzania

Contacts

Public ContactFrank Eric

National Institute for Medical Research-Muhimbili Center

frankerichy@yahoo.com+255-22-2152232

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026