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The role of epigenetic modifications in autism

The role of epigenetic modifications in autism spectrum disorder through DNA methylation

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR201705002282393
Enrollment
40
Registered
2017-05-10
Start date
2017-09-10
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nervous System Diseases Autism spectrum disorder

Interventions

DNA Methylation-and quantitative Real-time PCR (RT-PCR) Analysis
Gilliam Autism Rating Scale Arabic version:

Sponsors

the Vice Dean Research Office.
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: a. Inclusion criteria: All enrolled children with ASD will be: 1- Exhibit symptoms within the typical triad of autistic traits: communication impairment, social deficits, and ritualistic interests. 2- 2-6 years old. 3- Drug-naïve.

Exclusion criteria

Exclusion criteria: b. Exclusion criteria: The control subjects will also clinically examined by the psychiatrist to exclude any sub-clinical autistic features. Children with ASD and controls will excluded from the study if 2- They receive treatment for any reason. 3- -Endocrinological disease, mental retardation, communication disorder, psychotic disorder, attention deficit hyperactivity disorder and learning disorders seen in the children or their family members.

Design outcomes

Primary

MeasureTime frame
The difference in mean percentage of gene methylation.

Countries

Egypt

Contacts

Public ContactNesreen Mahmoud
drnessren82@yahoo.com01003248010

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026