Postmastectomy Pain

The pre-emptive use of pregabalin may reduce the incidence of postmasectomy pain syndrome following breast cancer surgery: a comparitive study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR201705002266194

Enrollment

210

Registered

2017-05-05

Start date

2015-09-09

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cancer Surgery post-mastectomy, pain , pregabalin, cancer

Interventions

group 1 (lyrica group)

group 2 (control group)

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Patients scheduled for elective breast surgery {either modified radical mastectomy(MRM) or conservative breast surgery (CBS)}combined with axillary dissection. ASA physical status I-II-III

Exclusion criteria

Exclusion criteria: -History of pregabalin or gabapentin allergy. -History of allergy to NSAIDs, morphine and paracetamol. -Pregnancy and lactation. -BMI > 40 kg/m^2. -Patients with major liver, renal, cardiorespiratory,endocrinal or haematological disorder. -Patients with preexisting pain which necessitates morphine at daily dose of 30 mg or more (or equivalent opioids). History of pregabalin intake in the preceding 3 months. -History of drug abuse. -Expected another breast surgery in the subsequent period. -Neuropsychiatric disorder.

Design outcomes

Primary

Measure	Time frame
Pain by using VAS	—

Secondary

Measure	Time frame
Post-mastectomy neuropathic pain using DN4;Side effects of pregabalin	—

Countries

Egypt

Contacts

Public ContactRaafat Mahfouz

Assistant Professor

dr_raafat2006@hotmail.com+201227411245

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026