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The Effect of Premedication With Intravenous Lornoxicam on Propofol Injection Pain At Induction of General Anaesthesia in Adults.

The Effect of Premedication With Intravenous Lornoxicam on Propofol Injection Pain at Induction of General Anaesthesia in Adults; A Randomised Placebo-Controlled Trial.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR201705002263637
Enrollment
156
Registered
2017-05-04
Start date
2017-08-01
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Propofol Injection Pain Anaesthesia

Interventions

Sponsors

Post Graduate Medical Education Programme
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Adult patients aged 18 to 65 years ASA physical status 1 and 2

Exclusion criteria

Exclusion criteria: Systemic Arterial Hypertension. Pregnancy. History of or active phlebitis/thrombophlebitis. Allergy or hypersensitivity (asthma, rhinitis, angioedema or urticaria) to lornoxicam and any of its excipients. Presence of any contraindication to NSAID use and particularly: Renal disease/renal impairment Hypersensitivity to any other NSAIDs Documented thrombocytopenia Gastro-intestinal bleeding, cerebrovascular bleeding or other bleeding disorders History of gastrointestinal bleeding or perforation, related to previous NSAIDs therapy Active or history of recurrent peptic ulcer/haemorrhage Severe hepatic impairment Severe heart failure. Patients already on other NSAID therapy. Language barriers in eexplaining study plan and obtaining consent. Difficult venous access (more than 2 attempts and/or <G20 cannula) Patients presenting for emergency surgery. Patients in pain. ASA physical status 3 and 4.

Design outcomes

Primary

MeasureTime frame
Intensity of propofol injection pain.

Secondary

MeasureTime frame
Incidence of propofol injection pain

Countries

Kenya

Contacts

Public ContactDennis Omari Onyancha

Anaesthesiology Resident

dennis.onyancha@aku.edu+254725944911

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Feb 4, 2026