Serum Folic Acid and Vitamin B12 in children with Idiopathic Epilepsy and their relation to Seizure Control and Cognitive functions

Assessment of Serum Folic Acid and Vitamin B12 in children with Idiopathic Epilepsy: Relation to Seizure Control and Cognitive functions

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR201704002060106

Enrollment

Registered

2017-02-22

Start date

2015-11-24

Completion date

Unknown

Last updated

2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Paediatrics idiopathic epilepsy

Interventions

folic acid and Vit B12 supplementation

Not intervention

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1-Drug resistant epilepsy: failure of adequate trials of two or more tolerated, appropriately chosen and used AED schedules (whether as monotherapies or in combination) to achieve sustained seizure freedom which is defined as freedom from all seizures, including auras, for at least three times the longest pre-treatment interseizure interval or 12 months. 2- Age: 5-18 years.

Exclusion criteria

Exclusion criteria: 1-Neurological, endocrinal or any systemic disease other than epilepsy. 2- Symptomatic and cryptogenic epilepsy. 3- Nutritional status impairments. (Z score ¿ -2SD) 4- Intake of nutritional supplements like vitamins and minerals.

Design outcomes

Primary

Measure	Time frame
decrease severity of epilepsy;decrease frequency of epilepsy;improve cognitive function test	—

Countries

Egypt

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Feb 4, 2026