Extending spinal anesthesia: dexmedetomidine plus fentanyl

Spinal anesthesia for Lengthy lower limb orthopaedic surgeries: Dexmeditiomidine plus Fentanyl

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR201703002122189

Enrollment

Registered

2017-03-22

Start date

2017-03-07

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Surgery lengthy lower limb surgeries Anaesthesia

Interventions

Dexmedetomidine Group

Dexmedetomidine plus Fentanyl Group

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: ¿ Patients scheduled for major lower limb orthopedic procedures exceeding 4 hours as bilateral both lower limbs procedures or two procedures in one lower limb with possible bone grafting. ¿ ASA I-III. ¿ Both sexes.

Exclusion criteria

Exclusion criteria: ¿ Patient refusal. ¿ Hypersensitivity to used anesthetics, ¿ General contraindications to spinal anesthesia, ¿ Cardiac, hepatic, renal or respiratory failure. ¿ Difficult communication.

Design outcomes

Primary

Measure	Time frame
¿The time till first pain sensation.;¿The time till Bromage score 0 (full leg movement)	—

Secondary

Measure	Time frame
¿ The required doses of intraoperative iv midazolam, fentanyl and propofol. ;¿ The rate of conversion to general anesthesia.;Intraoperative hemodynamics (MBP, HR) ;postoperative hemodynamics (MBP, HR) ;Maximum and minimum MBP and HR ;Required doses of atropine and ephedrine ;Incidence of using oxygen face mask (SaO2 less than 90%).;estimated blood loss ;The number of packed RBCs transfusion units;The volume of fluids administration ;Incidence of shivering, itching, nausea & vomiting;Incidence of sedation, shivering, itching, nausea & vomiting;The total morphine requirements ;Visual analogue scale (VAS);Duration of hospital stay;Patient satisfaction in a score (0 - 10)	—

Measure

Time frame

¿ The required doses of intraoperative iv midazolam, fentanyl and propofol. ;¿ The rate of conversion to general anesthesia.;Intraoperative hemodynamics (MBP, HR) ;postoperative hemodynamics (MBP, HR) ;Maximum and minimum MBP and HR ;Required doses of atropine and ephedrine ;Incidence of using oxygen face mask (SaO2 less than 90%).;estimated blood loss ;The number of packed RBCs transfusion units;The volume of fluids administration ;Incidence of shivering, itching, nausea & vomiting;Incidence of sedation, shivering, itching, nausea & vomiting;The total morphine requirements ;Visual analogue scale (VAS);Duration of hospital stay;Patient satisfaction in a score (0 - 10)

—

Countries

Egypt

Contacts

Public ContactAlaa Mazy

associate profesor of anesthesia and surgical intensive care

alaa_mazy@yahoo.com002050 01140065052

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026