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Efficacy of Magnesium Sulfate versus nalbuphine On Hemodynamic Responses To Orotracheal Intubation I

Efficacy of Magnesium Sulfate versus nalbuphine On Hemodynamic Responses To Orotracheal Intubation In Smokers

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR201703002107862
Enrollment
80
Registered
2017-03-17
Start date
2017-04-01
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Circulatory System smokers

Interventions

Group M ( n = 40): will receive magnesium sulfate 50 mg/kg in a total volume 100 ml of normal saline
Group N ( n = 40 ): will receive nalbuphine 0.2mg/kg in a total volume 100 ml of normal saline over

Sponsors

doaa rashwan
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: The study population will include inpatients of the involved departments including neurosurgery, general, urology, ENT, plastic and orthopedic surgery, both sex, selected randomly according to American Society of Anesthesiologists(ASA) grade I , between the ages of 18-50 years.

Exclusion criteria

Exclusion criteria: Exclusion criteria: - History or suspected difficult airway. - ASA physical status other than I. - Patients undergoing cardiac and neurosurgical procedures. - History of uncontrolled hypertension, myocardial ischemia, arrhythmias uncontrolled diabetes mellitus and cerebrovascular stroke. - Bronchial asthma. - Renal disease, liver dysfunction, pregnancy. - Patients on hypnotic or narcotic analgesic. - History of alcohol or drug abuse. - History of allergic reaction to opioids or any drug used in this study - Patients in whom the duration of laryngoscopy exceeded 30 seconds.

Design outcomes

Primary

MeasureTime frame
mean arterial blood pressure

Secondary

MeasureTime frame
heart rate

Countries

Egypt

Contacts

Public Contactdoaa rashwan

assitant professor

doaa_rashwan@hotmail.com00201011270763

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026