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Comparison Of Three Different Concentrations of Levobupivacaine for epidural labour analgesia: Clinical Effect and Pharmacokinetic Profile

Comparison Of Three Different Concentrations of Levobupivacaine for epidural labour analgesia: Clinical Effect and Pharmacokinetic Profile

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR201703002099811
Enrollment
60
Registered
2017-03-13
Start date
2015-11-11
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pregnancy and Childbirth Pregnancy

Interventions

¿ Group 1(n = 20): received epidural levobupivacaine 0.25%.
¿ Group 2(n = 20) : received epidural levobupivacaine 0.125%
¿ Group 3(n = 20): received epidural levobupivacaine 0.0625%.

Sponsors

Mohamed Shehta Asfour
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: The parturients were 20 to 40 years of age with vertex presentation and cervical dilatation less than 4 cm and having at least one contraction every 5 minutes, with gestational age more than 38 weeks

Exclusion criteria

Exclusion criteria: Parturients with hypertensive disorders of pregnancy (e.g., pre-eclampsia and eclampsia) or with a history of cardiac, liver, or kidney diseases were excluded from the study. Subjects with history of allergy to amide local anesthetics were also excluded.

Design outcomes

Primary

MeasureTime frame
1-Sensory block characteristics The onset of sensory block was determined by the time from injection of the epidural bolus dose till the occurrence of the first painless contraction and the achievement of VAS less than 3. The VAS was assessed at 30 minutes interval till delivery

Secondary

MeasureTime frame
The motor block The motor block was assessed according to the modified Bromage scale

Countries

Egypt

Contacts

Public Contactdoaa rashwan

Assitant professor

doaa_rashwan@hotmail.com00201011270763

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026