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Impact of HIV mother-infant pair clinics on 12 month retention

Assessing the impact of clinic days dedicated to providing HIV services for post-partum HIV-positive mothers and their HIV-exposed infants (¿Umoyo¿) on 12 month retention of infants

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR201702001970148
Enrollment
448
Registered
2017-01-13
Start date
2017-01-23
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

HIV/AIDS

Interventions

Umoyo Mother-Infant Pair (MIP) clinic
Standard of Care

Sponsors

Clinton Health Access Initiative
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: The following will be used as inclusion criteria for the program: ¿ For the retrospective study, HIV exposed infants (HEI)s will be included if they are 1) over the age of 6 weeks and under 3 months of age at 12 - 9 months before the launch of the MIP clinic program and 2) receiving services from a study facility. ¿ For the prospective study, HEIs will be included if they are 1) over the age of 6 weeks and under 3 months of age at the time of the launch of the MIP clinic and 2) receiving services from a study facility. ¿ For mother¿s questionnaire, women will be eligible for inclusion if they 1) are age 18 years or older, 2) are HIV-positive and 3) are receiving under-five services for their infant from a study site. At baseline, any woman meeting the other criteria and attending the under-five clinic will be eligible. At end line, women who have attended at least three Umoyo clinic days will be eligible.

Exclusion criteria

Exclusion criteria: The following will be used as exclusion criteria for the program: ¿ For the retrospective study, any HEI who is under age 6 weeks or over 3 months of age at 12 -9 months before the launch of the MIP program will be excluded. ¿ For the prospective study, any HEI who is under age 6 weeks or over 12 months of age at the time of the Umoyo clinic launch will be excluded. HEIs will also be excluded if they have already tested positive before age 12 months. ¿ For mother¿s exit questionnaire, women will be excluded if they 1) are under 18 years, 2) are not HIV-positive or 3) do not regularly receive under-five services for their infant from a study site. At end line, women will be excluded if they have not attended at least three Umoyo clinic days.

Design outcomes

Primary

MeasureTime frame
Change in the proportion of HIV-exposed infants retained in HIV care and treatment at 12 months of age.

Secondary

MeasureTime frame
Change in the proportion of HEIs with regular attendance as defined by monthly returns up to 6 months of age from 10 weeks to 6 months ;Change in the proportion of HEIs with regular attendance as defined by monthly returns up to 12 months of age from 10 weeks to 12 months ;Change in the proportion of HIV-positive children initiated on ART;Change in the proportion of HIV-positive children retained in care;6. Change in the proportion of HIV-positive mothers retained in care;Change in the proportion of HIV-Exposed infants initiated on TB Isoniazid (INH) prophylaxis ;Change in the proportion of HIV positive mothers testing for TB;Change in the proportion of HIV positive mothers receiving TB prophylaxis;Change in the proportion of HIV positive mothers on TB treatment;Difference in perceived social support of HIV-positive mothers among those in the intervention arm vs those in the control arm ;Difference in perceived stigma of HIV-positive mothers among those in the intervention arm vs those in the control arm ;Difference in knowledge of mothers on i) importance of retention and adherence ii) family planning among those in the intervention arm vs those in the control arm

Countries

Zambia

Contacts

Public ContactSandra Mudhune
smudhune@clintonhealthaccess.org+260960349758

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026