Ondansetron for post-spinal shivering

The role of ondansetron in prevention of post-spinal shivering (PSS) in the obstetric patient: a double blind randomized controlled trial.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR201612001896411

Enrollment

Registered

2016-11-29

Start date

2016-08-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pregnancy and Childbirth Post-spinal anesthesia shivering

Interventions

IV ondansetron

Normal Saline 0.9%

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: ASA physical status I or II Full term parturients 20 to 38 years old Scheduled for elective cesarean delivery under spinal anesthesia

Exclusion criteria

Exclusion criteria: Complicated pregnancy. Preoperative use of ondansetron or meperidine. Known allergy to the tested drug. Preoperative shivering. Preoperative fever (> 38°C). Hypo- or hyperthyroidism. Parkinson¿s or any extrapyramidal disease. Raynaud¿s syndrome. Intraoperative blood transfusion. Administration of opioids, clonidine, or vasodilator drugs.

Design outcomes

Primary

Measure	Time frame
Post-spinal shivering during elective cesarean delivery.	—

Secondary

Measure	Time frame
Nausea and vomiting	—

Countries

Egypt

Contacts

Public ContactAli Mokhtar

Lecturer of Anesthesia, Cairo University

alyaly4444@gmail.com01114999890

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026