induction of ovulation in polycystic ovary syndrome

Drospirenone containing combined oral contraceptive premedication before letrozole ovulation induction in clomiphene resistant PCOS, is it worth the wait?

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR201611001569368

Enrollment

100

Registered

2016-04-07

Start date

2016-05-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fertility-male Polycystic ovary syndrome

Interventions

drospirenone-ethinyl estradiol OCP pretreatment

Letrozole

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: clomiphene resistant anovulatory polycystic ovary patients, normal hysterosalpingogram or laparoscopy; no recorded history of pelvic surgery and/or pelvic inflammatory disease, normal male semen analysis

Exclusion criteria

Exclusion criteria: Presence of any infertility factors other than anovulatory PCOS, such as hyperprolactinemia, hypothalamic amenorrhea, premature ovarian failure, tubal or male factor infertility.

Design outcomes

Primary

Measure	Time frame
Ovulation	—

Secondary

Measure	Time frame
the mean number of follicles 14 mm or more ;Pregnancy rate	—

Countries

Egypt

Contacts

Public ContactHAITHAM HAMZA

Lecturer of Obstetrics and Gynecology - Faculty of Medicine - Menoufia university

haithamaboali80@gmail.com+201001359136

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026