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The use of 8% L-Arginine/calcium carbonate containing toothpaste in comparison to strontium acetate containing toothpaste in management of hypersensitive dentine in chronic periodontitis patients: A randomized controlled clinical trial

The use of 8% L-Arginine/calcium carbonate containing toothpaste in comparison to strontium acetate containing toothpaste in management of hypersensitive dentine in chronic periodontitis patients : A randomized-controlled clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR201610001824186
Enrollment
46
Registered
2016-10-16
Start date
2016-12-15
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral Health Dentin hypersensitivity in chronic periodontitis patients

Interventions

use of 8% L-Arginine/calcium carbonate containing toothpaste
use of strontium acetate containing toothpaste

Sponsors

abdallah hassan
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1)Slight to moderate chronic periodontitis patients diagnosed according to criteria of (¿Parameter on chronic periodontitis with slight to moderate loss of periodontal support. American Academy of Periodontology.,¿ 2000) as follows : ¿Probing pocket depths up to 6mm ¿Clinical attachment loss (CAL) up to 4mm ¿Class I (incipient) furcation involvement ¿Radiographic evidence of bone loss 2) At least 2 teeth presenting hypersensitive areas on facial surfaces of teeth with score 2 or 3 on the air sensitivity scale (Pepelassi et al., 2015) 3- Provision of written informed consent.

Exclusion criteria

Exclusion criteria: 1) Chipped teeth. 2) Defective restorations. 3) Deep dental caries or large restorations showing pulpal response. 4) Ongoing treatment with anti-inflammatory drugs. 5) Ongoing treatment for tooth hypersensitivity. 6) Pregnancy. 7) Uncontrolled metabolic diseases. 8) Psychiatric disorder. 9) Smoking

Design outcomes

Primary

MeasureTime frame
Pain relief This will be assessed using VAS that will be determined immediately before product use and then weekly for 8 weeks after the daily brushing with the test and control toothpastes following stimulus application using Visual Analog Scale (VAS)

Secondary

MeasureTime frame
Air blast sensitivity scores (Schiff et al., 1994);clinical periodontal parameters : Plaque index (PLI) (Löe, n.d.) ,Gingival index (GI) (Löe, n.d.);clinical periodontal parameters: Probing pocket depth (PPD),Clinical attachment level (CAL),Gingival recession (GR)

Countries

Egypt

Contacts

Public ContactAbdallah Hassan Mostafa

Masters Degree Student

dr.abdallah.hassan@gmail.com+201005682509

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026