Improving blood glucose control with a lunch-time dose of regular insulin in diabetic patients on twice daily mixed insulin

Assessment of the effect of mid-day pre-prandial bolus dose of regular insulin on glycemic control in diabetic patients on twice daily pre-mixed insulin therapy at Borg Al-Arab Hospital Internal Medicine Clinic: An open label randomized trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR201610001812290

Enrollment

120

Registered

2016-10-06

Start date

2016-10-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nutritional, Metabolic, Endocrine Diabetes

Interventions

Follow up only

Mid-day pre-prandial bolus dose of regular insulin

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Receiving twice daily insulin only Have access to a nearby pharmacy or a healthcare unit Have access to a phone Baseline HbA1c% of 8 or above

Exclusion criteria

Exclusion criteria: History of severe hyperglycemia, high risk of hyperglycemia and/or hyperglycemia unawareness Renal and hepatic patients Patients with uncontrolled ischemic heart disease Patients on beta-blockers, glucocorticoids, insulin secretagogues Pregnant and lactating women

Design outcomes

Primary

Measure	Time frame
Lowering HbA1c% to below 7	—

Secondary

Measure	Time frame
Reduction of the progression of diabetic nephropathy measured as albumin/creatinine ratio;Assessment on changed insulin ordering patterns and insulin shortages	—

Countries

Egypt

Contacts

Public ContactMaha Taha

Pharmacist

maha.abdullatief@gmail.com+20 11 1966 8318

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026