Gestational diabetes mellitus

Comparison of Metformin and Glyburide alone or in combination for treatment of gestational diabetes mellitus: a randomized clinical trial.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR201610001801760

Enrollment

120

Registered

2016-10-03

Start date

2016-10-16

Completion date

Unknown

Last updated

2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nutritional, Metabolic, Endocrine Pregnancy and Childbirth Gestational diabetes

Interventions

Metformin group

Glyburide group

Combined metformin and glyburide

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Women diagnosed with GDM based on the 2-hour 75 g oral glucose tolerance test (OGTT) using the criteria defined by the WHO were included.

Exclusion criteria

Exclusion criteria: Women with multiple pregnancies, having other associated medical disorder as heart disease, bronchial asthma & hypertension and pregnancies complicated by fetal malformations were excluded from the study.

Design outcomes

Primary

Measure	Time frame
Degree of glycemic control Maternal outcome Fetal-neonatal outcome.	—

Countries

Egypt

Contacts

Public ContactMohamed Rezk

Lecturer of Obstetrics and Gynecology-Faculty of Medicine-Menoufia University

m_rezk9207@yahoo.com00201006237186

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Feb 4, 2026