Dexmedetomidine versus magnesium sulphate as an adjuvant to rocuronium bromide, and local anesthetic mixture in peribulbar anaesthesia for viteroretin

Dexmedetomidine versus magnesium sulphate as an adjuvant to rocuronium bromide, and local anesthetic mixture in peribulbar anaesthesia for viteroretinal surgery

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR201608001667173

Enrollment

135

Registered

2016-06-09

Start date

2015-05-01

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Eye Diseases Surgery peribulbar anaesthesia in vitreoretinal surgery

Interventions

Group 1(C group)

Group 2( D group)

Group 3 ( M group)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 96 patients, aging (40-65y), (ASA I&II) of both sex presented for viteroretinal surgery under local anesthesia in Tanta University Hospital Ophthalmology department.

Exclusion criteria

Exclusion criteria: Patient with renal and liver diseases, Cardiovascular instability, Orthopnea, History of allergy to local anesthetics, Patient with coagulopathies and impaired platelet functions, Parkinsonism, claustrophobia, difficulty in communication, patients with high myopia, staphylomas, Local infection at the site of the block and extra¿ocular muscles or eyelid abnormalities will be excluded

Design outcomes

Primary

Measure	Time frame
To compare the effects of adding dexmedetomidine (DEX) or MgSO4 to rocuronium bromide as an adjuvant to local anesthesia mixture on the onset duration and degree of akinesia;To compare the effects of adding dexmedetomidine (DEX) or MgSO4 to rocuronium bromide as an adjuvant to local anesthesia mixture on the onset duration and degree of akinesia;To compare the effects of adding dexmedetomidine (DEX) or MgSO4 to rocuronium bromide as an adjuvant to local anesthesia mixture on the onset duration and degree of akinesia;To compare the effects of adding dexmedetomidine (DEX) or MgSO4 to rocuronium bromide as an adjuvant to local anesthesia mixture on the onset duration and degree of akinesia;To compare the effects of adding dexmedetomidine (DEX) or MgSO4 to rocuronium bromide as an adjuvant to local anesthesia mixture on the onset duration and degree of akinesia	—

Measure

Time frame

To compare the effects of adding dexmedetomidine (DEX) or MgSO4 to rocuronium bromide as an adjuvant to local anesthesia mixture on the onset duration and degree of akinesia;To compare the effects of adding dexmedetomidine (DEX) or MgSO4 to rocuronium bromide as an adjuvant to local anesthesia mixture on the onset duration and degree of akinesia;To compare the effects of adding dexmedetomidine (DEX) or MgSO4 to rocuronium bromide as an adjuvant to local anesthesia mixture on the onset duration and degree of akinesia;To compare the effects of adding dexmedetomidine (DEX) or MgSO4 to rocuronium bromide as an adjuvant to local anesthesia mixture on the onset duration and degree of akinesia;To compare the effects of adding dexmedetomidine (DEX) or MgSO4 to rocuronium bromide as an adjuvant to local anesthesia mixture on the onset duration and degree of akinesia

—

Secondary

Measure	Time frame
pain score and IOP in peribulbar anaesthesia in vitreoretinal surgery ;pain score and IOP in peribulbar anaesthesia in vitreoretinal surgery	—

Countries

Egypt

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026