Unblinded randomized control trial on Prophylactic Antibiotic Use in Gustilo II Open Tibia Fractures at Kenyatta National Hospital, Kenya

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR201606001689132

Enrollment

Registered

2016-06-21

Start date

2014-09-29

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Musculoskeletal Diseases Open fractures

Interventions

24-HOUR GROUP

5-DAY GROUP

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: ¿Patients with isolated Gustilo grade II open tibial fractures. ¿Patients aged between 18 and 80 years. Pediatric patients were excluded because of fixed dosage regimen in the study protocol.

Exclusion criteria

Exclusion criteria: ¿ Gustilo II open tibial fractures whose wounds could not be closed primarily after debridement ¿ Fractures that were not debrided within 24 hours of injury ¿ Non ¿ traumatic open tibia fractures such as pathological fractures ¿ Cigarette smokers ¿Patient with diabetes mellitus, HIV/AIDS, psychosis or chronic renal failure ¿Patients on corticosteroids or chemotherapy ¿Patients referred from other medical facilities where they had already received any form of treatment ¿Hemodynamically unstable patients ¿Patients who refused to give consent

Design outcomes

Primary

Measure	Time frame
INFECTION	—

Secondary

Measure	Time frame
Effect of duration to antibiotic administration on infectionj rate	—

Countries

Kenya

Contacts

Public ContactJOSHUA;MOSES ONDARI;MASIKA

UNIVERSITY OF NAIROBI;UNIVERSITY OF NAIROBI

jondari59@gmail.com;mosmasika@gmail.com+254722686298;+254737770306

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026