Comparative Study between the effects of lidocaine infusion, magnesium infusion or dexemedetomidine infusion on haemodynamic responses and postoperati

Comparative Study between the effects of lidocaine infusion, magnesium infusion or dexemedetomidine infusion on haemodynamic responses and postoperative outcome in laparoscopic cholecystectomy

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR201606001662120

Enrollment

Registered

2016-06-05

Start date

2015-01-01

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Surgery laparoscopic cholecystectomy Anaesthesia

Interventions

Group1:Lidocaine group (group L)

Group 2: Magnesium sulphate group (group M)

Group 3: Dexemedetomidine group (group D)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 96 adult patients, aging (25-65y),(ASA I&II) of both sex presented for laparoscopic cholecystectomy surgery in Tanta University Hospital

Exclusion criteria

Exclusion criteria: ¿ Cardiovascular instability (elderly & diabetics) ¿ Patient with chronic hypertension ¿ Sever cardiac deseases. AV block ¿ Patients on b-blockers or ca channel blockers ¿ History of allergy to local anesthetics. ¿ History of allergy to ¿2 agonist drugs . ¿ Patient with exaggerated hypertensive response (systolic<180, diastolic <110mmhg) ¿ Patients whose operation not completed laparoscopically and converted to open cholecystectomy, surgical time<180 min. ¿ Major liver or renal diseases ¿ Pregnancy ¿ Patients who received opioids or NSAIDS one week prior to surgery

Design outcomes

Primary

Measure	Time frame
is to compare the effects of using intraoperative dexemedetomidine, magnesium or lidocaine infusion on haemodynamic stress response to laryngoscopy , endotracheal intubation, creation of Pneumoperitoneum, and extubation in laparoscopic cholecystectomy.	—

Countries

Egypt

Contacts

Public ContactMona Mogahed

Lecturer of anesthesiaand surgical Intensive care Faculty of medicine Tanta University

monamogahedfr@hotmail.com00201145130150

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026