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Evaluation of postoperative pain and quantification of endotoxins in infected root canals

Evaluation of postoperative pain and quantification of endotoxins in infected root canals using antibiotic paste versus calcium hydroxide as intra-canal medication

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR201605001482394
Enrollment
Unknown
Registered
2016-02-22
Start date
2015-11-01
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral Health

Interventions

antibiotic paste
calcium hydroxide

Sponsors

faculty of oral and dental medicine, cairo university
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Age between 18-55 years old. Males or Females. Maxillary or mandibular single rooted premolar teeth. Non-Vital response of pulp tissue. Slight widening in lamina dura. Tenderness to percussion.

Exclusion criteria

Exclusion criteria: Pregnant females: Pain degree change may be due to hormonal change, and some medications are contra indicated. Patients who had received antibiotic treatment during the last 3 months. Patients having more than one tooth require root canal treatment. Teeth with periodontal probing depth > 4mm. Teeth that could not be isolated with a rubber dam. Fluctuant facial swelling (acute abscess) Previous root canal treatment.

Design outcomes

Primary

MeasureTime frame
Postoperative Pain—

Secondary

MeasureTime frame
quantification of endotoxins—

Countries

Egypt

Contacts

Public ContactGeraldine Ahmed

Assistant Professor

geraldine.ahmed@hotmail.com+201226322227

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026