Surgery
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients undergoing elective CABG aged 40-70 y.with 2-4 Vessel disease EF in the range of 25-50%.
Exclusion criteria
Exclusion criteria: age > 75 years, recent myocardial infarction, moderate to severe valvular lesions, hypertrophic obstructive cardiomyopathy (HOCM), pulmonary hypertension(mean pulmonary pressure >35mmhg), pericardial disease and infiltrative myocardial disease, patients with implantable pacemaker, emergency CABG, patients coming on inotropes, vasodilators or mechanical ventilation, significant pulmonary, hepatic or renal disease and oesophageal pathology.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The cardiac troponin I (cTnI) and creatine kinase isoenzyme MB (CK-MB), ;Ejection fraction (EF),fractional shortening(FS),Also we will assess signs of wall motion abnormalities(WMA). and cardiac index(CI) which will be measured by TEE.Also we will assess signs of wall motion abnormalities(WMA). ;Diastolic function indices will be tested by (trans-mitral diastolic doppler flow profile) and tissue doppler imaging (TDI) | — |
Countries
Egypt
Contacts
Professor in anesthesiology, Minoufiya faculty of medicine