The effect of goal directed fluid, inotrope and vasopressor therapy in preeclamptic patients undergoing caesarean section delivery under spinal anaest

The effect of goal directed fluid, inotrope and vasopressor therapy in preeclamptic patients undergoing caesarean section delivery under spinal anaesthesia with the use of a non-invasive finger cuff cardiac output monitor

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR201604001597634

Enrollment

Registered

2016-04-21

Start date

2016-05-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pregnancy and Childbirth Surgery

Interventions

Standard monitoring group

Cardiac output monitoring group

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Pregnant patients, 18 years of age and older, with the diagnosis of preeclampsia (as per the attending obstetrician), undergoing caesarean section delivery under spinal anaesthesia will be included in the study.

Exclusion criteria

Exclusion criteria: Patients: -with fetal distress -unable to give informed consent (including failure to understand explanation of the study in English language) -who decline to participate -already on vasopressor therapy prior to arrival in theatre -with antepartum haemorrhage -expected to have general anaesthesia -converted from spinal to general anaesthesia intraoperatively -where there is deviation from the study protocol

Design outcomes

Primary

Measure	Time frame
The primary outcome of the study is to document the effect of goal directed therapy using a non-invasive finger cuff cardiac output monitor on umbilical cord lactate in patients with preeclampsia, undergoing caesarean section delivery under spinal anaesthesia.	—

Countries

South Africa

Contacts

Public ContactCatherine Hosking

Specialist Anaesthesiologist

cath.hosking@gmail.com+27114884344

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026