The influence of Isoflurane versus combined isoflurane - epidural anesthesia on the immune response in patients undergoing surgery for colorectal canc

The influence of Isoflurane versus combined isoflurane - epidural anesthesia on the immune response in patients undergoing surgery for colorectal cancer

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR201604001580272

Enrollment

Registered

2016-04-11

Start date

2016-02-06

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cancer Surgery Anaesthesia

Interventions

isoflurane group

isoflurane-epidural group

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: above the age of 18 years, ASA I-II undergoing elective undergoing elective surgical intervention for colorectal cancer

Exclusion criteria

Exclusion criteria: 1- Emergency surgery 2- Renal dysfunction 3- Hepatic dysfunction 4- Cardiovascular diseases 5- Diabetes mellitus 6- Contraindications of epidural analgesia 7- Recent intake of corticosteroids or nonsteroidalantiinflammatory medications 8- Recent history of radiotherapy or chemotherapy

Design outcomes

Primary

Measure	Time frame
interleukins IL-6 , IL-10	—

Secondary

Measure	Time frame
postoperative complication (nausea and vomiting, respiratory depression, hypotension and bradycardia) ;hospital stay	—

Countries

Egypt

Contacts

Public ContactAhmed Essam Eldin

lecturer of anesthesiology and surgical intensive care, Tanta university

madamada6@gmail.com00201001802978

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026