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Comparison of Haemodynamic Effects of Propofol and Two Different Concentrations of Propofol-Ketamine Admixture: A Randomised Control Trial

Comparison of Haemodynamic Effects of Propofol and Two Different Concentrations of Propofol-Ketamine Admixture: A Randomised Control Trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR201603000964133
Enrollment
120
Registered
2014-12-08
Start date
2014-06-02
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anaesthesia

Interventions

Induction of anaethesia
Induction of Anaesthesia
Induction of anaesthesia

Sponsors

NECTAR
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: male and female patients aged between 18 and 50 years who are scheduled to undergo an elective general anaesthetic at Parirenyatwa and Harare Central Hospitals Patients will be recruited from general surgery, urology, gynecology and orthpeadic lists

Exclusion criteria

Exclusion criteria: ASA grade greater than III Pregnant women Hypertensive patients Patients with a history of drug or alcohol abuse Patients on medications that directly affect the CVS and neurological systems Patients with psychiatric diseases

Design outcomes

Primary

MeasureTime frame
1.To evaluate if ketofol has better a haemodynamic profile as an induction agent than propofol alone

Countries

Zimbabwe

Contacts

Public ContactPetros N Manyumwa

Jnr Registrar

pmanyumwa@yahoo.com+263 77506388

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026