HIV/AIDS Nutritional, Metabolic, Endocrine Paediatrics
Conditions
Interventions
aloe enriched whey protein
Chocolate drink mix powder
Sponsors
Armauer Hansen Research Institute
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: ¿Enrolled at the ALERT Hospital Pediatric HIV Clinic for greater than 1 year or with complete records transferred from another Pediatric HIV Clinic. ¿Age between 4-8 years ¿History of cART for >6 months. ¿Able/willing to return to clinic weekly to collect supplement and complete weekly health history form. ¿Able/willing to participate in every 3 month extended clinic visits and blood draws ¿Able/willing to ingest study supplements
Exclusion criteria
Exclusion criteria: ¿Any physical condition that precludes ingestion of food and study interventions ¿Suspected to have or with documented coinfection with TB disease ¿Any known cancers ¿Hx of hepatic or renal failure ¿Neurological/neuromuscular disease (cerebral palsy, muscular dystrophy, etc.) ¿Enrollment in another research study or project with medicinal or nutritional interventions ¿Children who have been on nutritional therapy (for severe wasting or PEM) in the last 6 months. ¿History of non-compliance with therapy ¿Another family or household member enrolled in same study ¿History of antihelminth treatment in last 3 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intestinal Fatty Acid Binding Protein levels | — |
Secondary
| Measure | Time frame |
|---|---|
| Endotoxin;inflammatory Cytokines, IL-1B, IL-6, TNFa;Immune activation markers;Immune reconstitution indicators and markers of recent thymic emigrants;Total Oxidation Status;Total Glutathione | — |
Countries
Ethiopia
Contacts
Public ContactMary Vander Wal
Graduate Student/Michigan State University
Outcome results
None listed