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Electrogustometric study of trigemino-gustatory interactions in humans

Trigemino-gustatory interactions: a randomized controlled clinical trial assessing the effects of selective anesthesia of trigeminal dental afferents on electrogustometric thresholds.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR201602001452260
Enrollment
313
Registered
2016-02-04
Start date
2011-12-05
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

oral diseaes and physiology

Interventions

Dental anesthesia

Sponsors

Cheikh Anta Diop University and Hospitalo-University Center
Lead Sponsor
Doctoral Scholl SEV
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: age between 18 and 70, no significant health issues (i.e. absence of cardiovascular disease, systemic disease, chronic immunosuppression, hemophilia or asthma) and no current medication intake, non-smokers, restorative or Endodontic Treatment required on mandibular premolars or molars, no more than two missing teeth within the hemimandibula, no more than eight posterior teeth absent in total, no history of chronic orofacial pain for at least three weeks before the start of the study, no oral mucosal abnormality (ulceration, lichen planus etc.), no tongue piercing and agreement to sign an informed consent.

Exclusion criteria

Exclusion criteria: Patients that do not fulfill the inclusion criteria, patients responding positively when EGM delivered no electrical current before anesthetic injection, patients presenting a lack of sensitivity in all loci before anesthetic injection or patients in which anesthesia was not effective after 30 minutes following injection.

Design outcomes

Primary

MeasureTime frame
The main result of this randomized controlled clinical trial is a statistically significant increase in EGMt ipsilateral to the side (p<0.05) of the anaesthetized of the inferior alveolar nerve (IAN) (trigeminal) at dorsal and posterior sites of the tongue following anesthesia.

Secondary

MeasureTime frame
Secondary results were: a statistically significant increases in the EGMt ipsilateral to the side of the anesthetized mandibular nerve (MdN) in all the ipsilateral sites of the tongue following anesthesia and a lack of variation in the EGMt following maxillary anesthesia in any site of the tongue surface.

Countries

Senegal

Contacts

Public ContactAichatou Sall

Praticien/University

dadychdent@orange.sn00221778161974

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026