Comparison between pressure regulated volume-controlled (PRVC) and volume-controlled (VC) ventilation on oxygenation parameters, airway pressures and

Comparison between pressure regulated volume-controlled (PRVC) and volume-controlled (VC) ventilation on oxygenation parameters, airway pressures and immune-modulation during thoracic surgery.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR201512001388104

Enrollment

Registered

2015-12-13

Start date

2015-12-15

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Respiratory Surgery One lung ventilation during thoracic surgery

Interventions

PRVC group

VC group

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: adult patients ASA I-III undergoing elective open thoracic surgery using one lung ventilation.

Exclusion criteria

Exclusion criteria: Preoperative exclusion criteria will include patient refusal, significant lung diseases {forced expiratory volume in 1 s (FEV1) or vital capacity (VC) 30 mm Hg, hepatic or renal disease, coagulation disorders or a history of pre-operative immuno-suppressant medications. Intraoperative exclusion criteria will include inability to maintain an appropriate arterial oxygen saturation(SpO2) and end-tidal carbon dioxide (EtCO2), inability to keep stable mechanical ventilation settings for 30 min, , abnormal surgical complications, and prolonged hemodynamic instability

Design outcomes

Primary

Measure	Time frame
arterial, and central venous blood gases, Pa O2/FIO2 ratio, dead space volume/tidal volume (VD/VT) ratio, peak inspiratory pressure (Ppeak), mean inspiratory pressure (Pmean), and plateau inspiratory pressure (Plateau),	—

Countries

Egypt

Contacts

Public Contactkhaled mahmoud

Professor in anesthesiology, Minoufiya faculty of medicine

mahmoudk16@yahoo.com+201224884620

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026