Ondansetron for Children with Vomiting in Acute Diarrheal Illness

EFFECT OF ONDANSETRON IN CHILDREN PRESENTING WITH ACUTE DIARRHOEAL ILLNESS AND VOMITING WITH SOME DEHYDRATION

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR201512001284912

Enrollment

114

Registered

2015-09-28

Start date

2015-01-01

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Paediatrics Acute Diarrhoeal Illness

Interventions

Ondansetron

Placebo

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Age 6 to 59 months 2. Clinical diagnosis of acute diarrhoea 3. 3 or more episodes of non-bilious, non-bloody vomiting in the preceding 24hrs 4. Children classified with some dehydration 5. Informed written consent from caregiver

Exclusion criteria

Exclusion criteria: 1. Treatment with an antiemetic in the previous 24 hours 2. Clinical diagnosis of dysentery 3. Underlying chronic illness e.g. Cardiac disease, Liver or Renal failure, malignancy etc. 4. Severely Malnourished children 5. Known history of hypersensitivity to ondansetron

Design outcomes

Primary

Measure	Time frame
Hospitalization;ORT Failure	—

Secondary

Measure	Time frame
Hospital Revisit;Emesis Episodes;Diarrhoeal Episodes	—

Countries

Kenya

Contacts

Public ContactLaving Ahmed

Lecturer

arlaving@yahoo.com0722644122

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026