Effect of anesthetics on left ventricular diastolic function in patient with diastolic dysfunction undergoing CABG

Effect of propofol versus isoflurane on left ventricular diastolic function in patient with diastolic dysfunction undergoing coronary artery bypass grafting

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR201511001243895

Enrollment

Registered

2015-08-18

Start date

2015-01-05

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Circulatory System Surgery coronary artery bypass grafting

Interventions

Propofol

Isoflurane

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 60 ASA class II or III patients scheduled for CABG surgery by using CPB

Exclusion criteria

Exclusion criteria: age > 75 years, left ventricular ejection fraction (LVEF) < 55%, pre-existing severe LV hypertrophy, cardiomyopathies, pre-existing valvular heart disease, grade II (pseudo-normal filling) and grade III (restrictive filling) diastolic dysfunction, preoperative atrial fibrillation , pericardial disease, emergency CABG, significant pulmonary disease and esophageal pathology.

Design outcomes

Primary

Measure	Time frame
trans-mitral diastolic doppler flow profile, tissue doppler imaging (TDI) , pulmonary venous flow velocity	—

Secondary

Measure	Time frame
hemodynamic data (HR, MAP and CVP)	—

Countries

Egypt

Contacts

Public Contactkhaled Mahmoud

Professor in anesthesiology, Minoufiya faculty of medicine

mahmoudk16@yahoo.com+201224884620

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026