A Randomized Controlled Trial Comparing Selective Laser Trabeculoplasty and Timolol for Treatment of Glaucoma in Tanzania

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR201508001235339

Enrollment

360

Registered

2015-08-12

Start date

2015-08-17

Completion date

Unknown

Last updated

2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Eye Diseases Glaucoma

Interventions

Selective Laser Trabeculoplasty

Timolol eye drops

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: IOP above 21mmHg in the study eye Open chamber angle with sufficient visualisation of angle structures (Shaffer II or more) on Gonioscopy Clear media (cornea, anterior chamber) to visualise the chamber angle Glaucomatous optic disc changes (structural changes due to glaucoma) with or without glaucomatous visual field defects (functional changes due to glaucoma) or high risk chronic open-angle glaucoma suspect. Ability to provide informed consent Willingness to return for regular follow-up visits Pseudophakic patients will be enrolled if the chamber angle is open and the anterior segment shows no signs of inflammation.

Exclusion criteria

Exclusion criteria: No perception of light History of previous glaucoma surgery including other laser treatment History of previous uveitis Neovascular glaucoma Physical inability to administer topical treatment Age below 18 years. Pregnant women History of asthma, bradycardia, previous heart failure, hypersensitivity to beta-blockers or systemic use of beta-blockers.

Design outcomes

Primary

Measure	Time frame
Success defined as intraocular pressure below or equal to target pressure	—

Secondary

Measure	Time frame
Success rates with fixed thresholds and mean intraocular pressure;Visual acuity and visual field;Complication rates;Quality of life and other patient reported outcomes;Cost analysis;Qualitative analysis;Structural changes of the optic disc, cornea or other affected structures	—
Structural changes of the optic disc, cornea or other affected structures;Success rates with fixed thresholds and mean intraocular pressure;Visual acuity and visual field;Complication rates;Quality of life and other patient reported outcomes;Cost analysis;Qualitative analysis	—

Countries

Tanzania

Contacts

Public ContactHeiko Philippin

Glaucoma Consultant

philippin@gmx.de+255 (0) 272754890

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Feb 21, 2026