Effect of sodium bicarbonate on the lower respiratory tract pathogens

Effect of bronchoalveolar lavage with sodium bicarbonate 8.4 % on the retrieved lower respiratory tract pathogens

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR201508001233590

Enrollment

Registered

2015-08-11

Start date

2014-03-12

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Respiratory lower respiratory tract infections

Interventions

BAL saline 0.9% followed by BAL withSB 8.4%

BAL with only 10 ml of saline (sample A) followed by BAL with 50 ml SB 8.4% (sample B) followed by B

BAL with saline

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: patients with clinical and radiological pictures suggestive of lower respiratory tract infections (LRTI) age more than 18 years fit for fiberoptic bronchoscopy (FOB)

Exclusion criteria

Exclusion criteria: Patients with no radiological signs of LRTI those unfit for FOB

Design outcomes

Primary

Measure	Time frame
Mean pH for saline versus bicarbonate samples;microorganisms retrieved from BAL samples of the studied groups;CFU for bacteria and fungi retrieved from BAL samples ;Ziehl¿Neelsen stain and tuberculosis culture	—

Secondary

Measure	Time frame
Safety of the procedure:	—

Countries

Egypt

Contacts

Public ContactDina Abouelkheir AbdAlla

Lecturer of Chest Medicine- Faculty of Medicine ¿ Mansoura University

dkhair@mans.edu.eg+2 01009976012

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026