Choukroun¿s platelet-rich fibrin (PRF) as an autogenous graft biomaterial in pre-implant surgery: a randomised human histomorphometric split-mouth stu

Choukroun¿s platelet-rich fibrin (PRF) as an autogenous graft biomaterial in pre-implant surgery: a randomised human histomorphometric split-mouth study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR201508001230312

Enrollment

Registered

2015-08-11

Start date

2013-05-30

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Surgery pre-implant surgery

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Aim: This study aimed to test the null hypothesis that PRF as an immediate post-extraction graft material produces bone histomorphometrically no different to bone derived from healing without intervention. Methods and materials: A split-mouth human biopsy investigation was carried out, deriving bone cores from randomized tooth extraction sites ¿ comparing bone derived from PRF to bone having healed without intervention.

Exclusion criteria

Exclusion criteria: ¿ Failing to meet accepted practice indications for treatment of missing teeth by dental implant supported restorations ¿ Active periodontitis ¿ Loss of the buccal, lingual, or palatal bone plate during tooth extraction ¿ Mandibular teeth ¿ Molar teeth (multi-rooted first premolar teeth were included, if the interseptal bone within the socket was not shallower than 7 mm ¿ verifiable with the trephine bur at extraction visit) ¿ Aged 18 or under ¿ Smoking ¿ Not consenting to participate in the study ¿ Unmotivated and unable to comply with the study¿s follow up requirements

Countries

United States of America

Outcome results