Comparison between Trabeculectomy surgery outcomes with two different methods of application of Mitomycin C

A comparison of Trabeculectomy surgery outcomes in adutls with Mitomycin C applied by intra Tenon's injection versus Sponge method

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR201508001201385

Enrollment

100

Registered

2015-07-14

Start date

2015-05-01

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Eye Diseases Surgery Glaucoma

Interventions

Sponge MMC

Intra Tenon's MMC

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1- Adult Patients undergoing trabeculectomy surgery with the clinical diagnosis of glaucoma in and over 18 years of age. 2- Children with congenital glaucoma, undergoing trabeculectomy surgery.

Exclusion criteria

Exclusion criteria: 1- Prior glaucoma surgery except trabecular or iris based laser procedure 2- Prior Cyclodestructive procedures 3-Abnormal cornea that would make IOP measurements unreliable 4- Contraindication to the use of Mitomycin C (Pregnancy, Corneal or scleral chronic disease , connective tissue disease) 5- Inability to attend follow up visits 6- Intraocular pressure greater than 21 at postoperative week 1 (represents primary failure of the trabeculectomy)

Design outcomes

Primary

Measure	Time frame
Intraocular pressure (IOP)	—

Secondary

Measure	Time frame
1- Bleb grading and presence of cystic blebs or encapsulation;2- adverse reactions	—

Countries

Egypt

Contacts

Public ContactMahmoud Rateb

Lecturer of Ophthalmology

rateb.cvec@gmail.com+201008348480

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026