Pregnancy and Childbirth Surgery pre- eclampsia, caesarean delivery
Conditions
Interventions
Dexmedetomidine infusion
Fentanyl
Sponsors
Rehab Said Elkalla
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: women aged ¿ 18 years, with severe pre-eclampsia undergoing elective caesarean deliveries will be enrolled. Pre-eclampsia will be regarded as severe {if the systolic arterial pressure (SAP) on admission exceed 160 mm Hg, the diastolic pressure exceed 110 mm Hg, or both, obtained on at least two separate occasions, or if the patient has symptoms of imminent eclampsia (severe headache, visual disturbance, epigastric pain, hyper-reflexia, or vomiting), and proteinuria on urine dipstick was 3+ or worse}.
Exclusion criteria
Exclusion criteria: suspected difficult intubation (mallanpati score 3-4), history of exacerbated chronic medical disease, diabetes mellitus, morbid obesity, allergy to drugs used, and known fetal anomalies. Patients will be excluded from analysis if tracheal intubation takes longer than 40 seconds or if more than 1 attempt will be required for successful intubation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| evaluate the effects of dexmedetomidine and fentanyl on the changes in blood pressure and heart rate observed during laryngoscopy and tracheal intubation in pre-eclamptic patients | — |
Secondary
| Measure | Time frame |
|---|---|
| neonatal outcome | — |
Countries
Egypt
Contacts
Public ContactMohammad ;Mohammad Abdullah;Abdullah
Lecturer of anesthesiology and surgical intensive care;Lecturer of anesthesiology and surgical intensive care
Outcome results
None listed