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200µg versus 400µg sublingual misoprostol in prevention of postpartum haemorrhage

COMPARATIVE EFFECTIVENESS OF 200µG VERSUS 400µG OF SUBLINGUAL MISOPROSTOL FOR THE PREVENTION OF PRIMARY POSTPARTUM HAEMORRHAGE: A RANDOMISED CONTROLLED TRIAL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR201505001107182
Enrollment
Unknown
Registered
2015-04-16
Start date
2011-04-21
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pregnancy and Childbirth POSTPARTUM HAEMORRHAGE

Interventions

Sponsors

Dr I.A Ugwu
Lead Sponsor
Dr O.O Enabor
Collaborator
Anayochukwu-Ugwu N.N
Collaborator
Dr A.B Adeyemi
Collaborator
Prof O.O Olayemi
Collaborator

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Women at term with singleton pregnancy in active phase labour, or women undergoing induction of labour and with anticipated spontaneous vaginal delivery

Exclusion criteria

Exclusion criteria: contraindications for use of misoprostol such as asthma paturients undergoing caesarean section presence of coagulation disorders pre-eclampsia and other hypertensive diseases in pregnancy anaemia conditions requiring prophylactic oxytocin infusion after delivery such as grandmultiparity, multiple pregnancy, polyhydramnios and coexisiting uterine fibroids previous history of postpartum haemorrhage history of anteparturm haemorrhage Refusal or withdrawal of consent

Design outcomes

Primary

MeasureTime frame
amount of postpartum blood loss;presence of notable side effects of misoprostol;occurence of postpartum haemorrhage

Secondary

MeasureTime frame
change in packed cell volume;need for blood transfusion

Countries

Nigeria

Contacts

Public ContactTimothy Oluwasola

Lecturer / Consultant Obstetrician & Gynaecologist

sesanoluwasola@yahoo.com+2348033384064

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Mar 2, 2026