Comparative effect of propofol versus sevoflurane on renal ischemia/reperfusion injury after elective open abdominal aortic aneurysm repair. A random

Comparative effect of propofol versus sevoflurane on renal ischemia/reperfusion injury after elective open abdominal aortic aneurysm repair. A randomized trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR201505001095139

Enrollment

Registered

2015-04-02

Start date

2012-02-05

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Circulatory System Surgery renal ischemia/reperfusion injury Anaesthesia

Interventions

propofol group

sevoflurane group

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 50 ASA class II or III patients scheduled for elective infra-renal AAA repair.

Exclusion criteria

Exclusion criteria: Patients were excluded from the study if they needed concomitant procedures other than AAA repair, had experienced an acute coronary syndrome within 3 months, or were >85 years of age.

Design outcomes

Primary

Measure	Time frame
Urinary specific kidney proteins (N-acetyl-beta-Dglucosamidase, alpha-1-microglobulin, glutathione transferase-pi, glutathione transferase-alpha);creatinine clearance and serum cystatin	—

Secondary

Measure	Time frame
Serum pro-inflammatory cytokines (tumor necrosis factor-¿ and interleukin 1-¿)	—

Countries

Egypt

Contacts

Public Contactkhaled mahmoud

Professor in anesthesiology, Minoufiya University, Egypt

mahmoudk16@yahoo.com+201224884620

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026