Dexmedetomidine decreases the required concentration of bupivacaine for ultrasound-guided transversus abdominis plane block in pediatric patients

Dexmedetomidine decreases the required concentration of bupivacaine for ultrasound-guided transversus abdominis plane block in pediatric patients: a randomized double-blind up-down dose-finding study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR201502001009132

Enrollment

Registered

2015-01-24

Start date

2015-03-01

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Surgery Paediatrics ultrasound-guided transversus abdominis plane block in pediatric patients Anaesthesia

Interventions

Group BD (Bupivacaine plus 2µg/kg dexmedetomidine).

GroupB (TAP Bupivacaine)

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: patients aged between 1-6years ASA I &II undergoing hernia repair or hydrocelectomy

Exclusion criteria

Exclusion criteria: local infection of the abdominal wall allergic to amide local anesthetics blood clotting disorders neurological, neuromuscular or psychiatric disorders severe renal, hepatic, respiratory, or cardiac diseases

Design outcomes

Primary

Measure	Time frame
The primary endpoint of the study is the minimum local anesthetic concentration (MLAC)	—

Secondary

Measure	Time frame
pain score measured by FLACC pain score;postoperative sedation	—

Countries

Egypt

Contacts

Public Contactdoaa abou alia

Assistant Professor Department of Anaesthesia and Surgical Intensive Care, Faculty of Medicine

daboalia@yahoo.com01227392473

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026