Anti-inflammatory dietary combo in overweight and obese women with polycystic ovary syndrome

The effects of anti-inflammatory diet - in the context of lifestyle modification - with or without the use of metformin, on metabolic, endocrine, inflammatory and reproductive profiles in overweight and obese women with polycystic ovary syndrome

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR201502001001110

Enrollment

150

Registered

2015-01-18

Start date

2012-03-01

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fertility-female polycystic ovary syndrome

Interventions

Lifestyle modification (diet and exercise)

Lifestyle modification + Metformatin

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Non-pregnant, overweight and obese adult females with PCOS, aged 20 ¿ 40 years

Exclusion criteria

Exclusion criteria: The following subjects were excluded from the study: ¿ Subjects having type 1 or type 2 diabetes. ¿ Subjects receiving metformin within the last month. ¿ Subjects receiving ovulation induction medications within the last month. ¿ Subjects following a diet regimen within the last month.

Design outcomes

Primary

Measure	Time frame
To assess the effects of lifestyle modification with or without metformin on anthropometric, metabolic, endocrine and inflammatory markers in overweight and obese women with polycystic ovary syndrome.	—

Secondary

Measure	Time frame
To assess the effects of dietary recalibration, exercise and behavioural modification with or without metformin on regain of menstrual cyclicity and spontaneous pregnancy rates, and to compare the value of Acute-phase serum amyloid A as a surrogate marker for prognostic evaluation of the metabokic profile in overwight and obese women with PCOS in relation to C-reactive protein (CRP)	—

Countries

Egypt

Contacts

Public ContactAmany Salama

Women's Health and Nutrition Clinic

amanysalama@hotmial.com+1 1001637394

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026