Malaria
Conditions
Interventions
ACT plus primaquine group
ACT treatment Group
Sponsors
University Cheikh Anta DIOP of Dakar, Department of Medical Parasitology.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Adult patients with acute uncomplicated P. falciparum malaria; 2. P. falciparum monospecific infection with parasite density ranged from 1000 to 100 000 trophozoite/¿L. 3. Willingness to participate in the planed study investigations and to remain in the study area for the duration of the study; 4. Participants informed consent; 5. Absence of known chronic illness such as hypertension, diabetes, renal and liver disease.
Exclusion criteria
Exclusion criteria: 1. Known allergy to the study medications; 2. Presence of severe anaemia (haemoglobin < 8 g/dl) at enrolment; 3. Pregnancy, or breastfeeding.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean haemoglobin difference from day 0 to day 7 after treatment with ACT and primaquine. | — |
Secondary
| Measure | Time frame |
|---|---|
| Mean haemoglobin level at day 14 of follow up in each treatment arm.;Mean haemoglobin level at day 28 of follow up in each treatment arm. | — |
Countries
Senegal
Contacts
Public ContactSamba Cor Sarr
Head of National ethical Committee
Outcome results
None listed