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Antagonist versus agonist protocols: in patients with polycystic ovary syndrome treated for ICSI cycles

Fixed gonadotrophin releasing hormone antagonist protocol versus gonadotrophin releasing hormone agonist : long protocol in patients with polycystic ovary syndrome treated for ICSI cycles.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR201411000933365
Enrollment
200
Registered
2014-11-08
Start date
2014-06-01
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fertility-female Infertility in PCOS patients

Interventions

Sponsors

Obestetrics and Gynaecology Department, Faculty of Medicine, University of Alexandria
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1. Normogonadotrophic females ( tubal factor ¿ unexplained infertility) 2.PCOS patients fulfilling roterdam criteria of PCOS). Diagnosis depends on two of the following criteria only: Clinical and/or biochemical evidence of hyperandrogenism with exclusion of other causes of androgen excess. Oligo or anovulation. Polycystic ovaries by ultrasound(ovarian volume>12cc with 10 or more cysts 2- 8mm in diameter arranged around echo 3.Body mass index(BMI)<35.

Exclusion criteria

Exclusion criteria: critria:1.Hypogonadotrophic patients 2. Hypergonadotrophic patients. 3.BMI>35 4.Endometriosis 5.Poor response in previous ICSI cycles 6.uterine factor infertility. 7.Severe male factor infertility. 8.History of ovarian surgery.

Design outcomes

Primary

MeasureTime frame
Total number of oocytes;The number of mature oocytes per cycle of induction;Serum estradiol and progesterone level on the day of HcG.;Implantation rate(number of sacs per number of embryo transfer).

Secondary

MeasureTime frame
Clinical pregnancy

Countries

Egypt

Contacts

Public ContactElsayedamr Basma

Patient Information Manager

elsayedamr@yahoo.com002-01223106023

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Feb 4, 2026