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managment of oligohydramnios

Sildenafil Citrate Therapy for Oligohydramnios

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR201411000920150
Enrollment
184
Registered
2014-10-28
Start date
2014-11-01
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

oligohydramnios

Interventions

sildenafil citrate
Fluid therapy

Sponsors

menoufiya university hospital
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Pregnant women will be included if they are of any age, any parity, carrying a singleton pregnancy, at a gestational age (GA) 30 weeks or more (based on the last menstrual period and confirmed by the results of ultrasound or determined through early pregnancy sonography), they have an AFI ¿ 5, no pregnancy complications such as preeclampsia, gestational hypertension, or diabetes, no prior history of kidney, lung, and heart disease (the use of bolus-fluid therapy is contraindicated in these patients), and intact fetal membranes.

Exclusion criteria

Exclusion criteria: Mothers treated with prostaglandin synthetase inhibitors, well established labor, evidence of fetal distress (non-reactive non stress test), or fetal complications (intrauterine growth retardation or obvious fetal anomalies) are considered exclusion criteria.

Design outcomes

Primary

MeasureTime frame
the values of AFI before and after therapy in each group and between both groups.

Countries

Egypt

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026