Expanding Contraceptive Health Options (ECHO-1): a randomised clinical trial of injectable contraceptives versus the IUD

A randomised clinical trial of the efficacy, safety and acceptability of injectable contraceptives versus the IUD

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR201409000880157

Enrollment

7000

Registered

2014-09-04

Start date

2009-07-06

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pregnancy and Childbirth contraception, reproductive health

Interventions

Copper 380 IUD

Injectable contraceptive (DMPA or NET)

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Women undergoing pregnancy termination who consented to participation post-termination, with random allocation of contraception methods.

Exclusion criteria

Exclusion criteria: Not consenting. Contraindications to DMPA, NET or IUD.

Design outcomes

Primary

Measure	Time frame
unplanned pregnancy	—

Secondary

Measure	Time frame
HIV acquisition;HIV disease progression;Menstrual effects;Other effects, including sexual desire, weight gain, depression and condom use;Discontinuation	—

Countries

South Africa

Contacts

Public ContactMandisa Singata

Project Manager

mandisa.singata@gmail.com+27 43 708 2353

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026